Drug-DNA interactions
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Drug-DNA interactions structure and spectra by Kazuo Nakamoto

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Published by John Wiley & Sons in Hoboken, N.J .
Written in English

Subjects:

  • DNA-drug interactions -- Research -- Methodology,
  • DNA -- Spectra,
  • Drugs -- Spectra,
  • DNA -- drug effects,
  • Chemistry, Analytical -- methods,
  • DNA -- chemistry,
  • Pharmaceutical Preparations -- chemistry,
  • Structure-Activity Relationship

Book details:

Edition Notes

Includes index.

StatementKazuo Nakamoto, Masamichi Tsuboi, Gary D. Strahan.
ContributionsTsuboi, Masamichi, 1925-, Strahan, Gary D.
Classifications
LC ClassificationsQP624.75.D77 N35 2008
The Physical Object
Paginationp. ;
ID Numbers
Open LibraryOL18278894M
ISBN 109780471786269
LC Control Number2007050457

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Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this tand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and. This well-illustrated book of chapters written by leading experts will be extremely useful for postgraduates, post-doctoral fellows, established scientists, and some clinicians interested in the field of drug-DNA interactions. this update will be welcomed by students and justifies replacement.” (Omer Iqbal, Doody’s Review Service, May. The finding of the direct binding of quinolone to DNA has triggered more detailed investigations on the role of drug–DNA interaction in the enzyme inhibition. The binding of [3 H]norfloxacin to supercoiled ColEl DNA (as illustrated in Fig. 3) demonstrates a specific type of drug binding based on the following observations: (1) the binding is saturable and takes place at the drug's.

Physico-Chemical Studies on Anthracycline-DNA Interactions: Analysis of Equilibrium, Kinetic and Structural Data H. Fritzsche and A. Walter The Polyelectrolyte Correction to Site Exclusion Numbers in Drug-DNA Binding Richard A. G. Friedman and Gerald S. Manning Statistical Mechanics of Nucleic Acid Helix Formation and the Intercalation of Ligands. In Drug-DNA Interaction Protocols, Second Edition, expert researchers explore these compounds, revealing how a deeper understanding of the structure of DNA, along with an improved ability to manipulate it, has led to much progress in recent years. Chapters describe a new arsenal of techniques for probing the interactions between drugs and DNA. Authoritative and current, Drug-DNA Interaction Protocols, Second Edition, is a critical volume that includes a wide range of chapters, which together provide methods for assessing the strength and mode of binding, the sequence selectivity, and the effect on biological systems. This well-illustrated book of chapters written by leading experts will be extremely useful for postgraduates, post-doctoral fellows, established scientists, and some clinicians interested in the field of drug-DNA interactions. this update will be welcomed by students and justifies replacement.” (Omer Iqbal, Doody’s Review Service, May 5/5(1).